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Seann Mulcahy

Assistant Professor

Contact Information:

smulcahy@providence.edu
401-865-1280
Albertus Magnus Hall 319

Education:

Postdoctoral Research - Boston University
Postdoctoral Research - Yale University
Ph.D. - University of Pennsylvania

Area(s) of Expertise:

Organic chemistry, medicinal chemistry, chemical biology, chemical education

Awards and Honors:

Faculty Early Career Development Award - NIH RI-INBRE
Medical Research Grant - Rhode Island Foundation
Pilot Student Training Award - NIH RI-INBRE
Division of Organic Chemistry Travel Award - American Chemical Society

Selected Publications:

Roggero, Chad., Giulietti, Jennifer., Mulcahy, Seann. (2014). Efficient synthesis of eudistomin U and evaluation of its cytotoxicity. Bioorganic and Medicinal Chemistry Letters, 24 (15), 3549-3551.

Mulcahy, Seann., Varelas, Jonathan. (2013). Three-step synthesis of an annulated β-carboline via palladium catalysis. Tetrahedron Letters, 54 (48), 6599-6601.

Mulcahy, Seann., Woo, Christina., Ding, Weidong., Ellestad, George., Herzon, Seth. (2012). Characterization of a Reductively-Activated Elimination Pathway Relevant to the Biological Chemistry of the Kinamycins and Lomaiviticins. Chemical Science, 3, 1070-1074.

Gong, Lei., Mulcahy, Seann., Devarajan, Deepa., Harms, Klaus., Frenking, Gernot., Meggers, Eric. (2010). Chiral Salicyloxazolines as Auxiliaries for the Asymmetric Synthesis of Ruthenium Polypyridyl Complexes. Inorganic Chemistry, 49, 7692-7699.

Mulcahy, Seann., Gruendler, Katharina., Frias, Corazon., Prokop, Aram., Meggers, Eric. (2010). Discovery of a Strongly Apoptotic Ruthenium Complex Through Combinatorial Coordination Chemistry. Dalton Transactions, 39, 8177-8182.

Recent Presentations:

Mulcahy, Seann., Roggero, Chad., Giulietti, Jennifer., 248th National Meeting of the American Chemical Society, American Chemical Society, San Francisco, CA, "Suzuki Cross Coupling Strategy for the Synthesis of 1-Aryl and 1-Heteroaryl Eudistomin U Analogs". August, 2014.

Varelas, Jonathan., O'Donnell, Michael., Khanal, Satyam., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Convenient synthesis of annulated β-carbolines via transition metal-catalyzed [2+2+2] cyclization". March, 2014.

Schwarzer, Cody., Szeto, Howard., Gale-Day, Zachary., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Diastereoselective synthesis of unnatural alkaloids". March, 2014.

Roggero, Chad., Giulietti, Jennifer., Mulcahy, Seann., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Synthesis of β-carboline natural products via divergent palladium catalysis". March, 2014.

Giulietti, Jennifer., Roggero, Chad., Mulcahy, Seann., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Synthesis, cytotoxicity, and DNA-binding studies of the natural product eudistomin U". March, 2014.


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